Objective: To analyze the therapeutic effects of minimally invasive percutaneous plate osteosynthesis (MIPPO) and traditional open reduction and internal fixation (ORIF) for humeral shaft fractures (middle and lower segments). Methods: A total of 38 patients with humeral shaft fractures (middle and lower segments) admitted to the hospital from May 2022 to May 2025 were selected and evenly divided into two groups using a random number table. The experimental group received MIPPO treatment, while the reference group received ORIF treatment. The postoperative complication rates, upper limb function scores, and perioperative indicators were compared between the two groups. Results: The experimental group had a lower postoperative complication rate, higher upper limb function scores at one month postoperatively, and superior perioperative indicators compared to the reference group (P < 0.05). Conclusion: MIPPO treatment for patients with humeral shaft fractures (middle and lower segments) results in fewer postoperative complications than ORIF, with superior upper limb functional recovery and postoperative rehabilitation quality, demonstrating significant surgical advantages.
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