Advances in Obstetrics and Gynecology Research

Observation on the Effectiveness of Hysteroscopy Combined with B-Ultrasound in Diagnosing Uterine Incision Diverticulum after Cesarean Section

Qiumin Li, Juan Chen — Thu, 13 Jun 2024 16:59:55 +0800

Objective: To analyze the positive significance of employing hysteroscopy and B-ultrasound together in diagnosing uterine incision diverticulum after cesarean section. Methods: The study was conducted at the Shaanxi Provincial People’s Hospital from February 2023 to February 2024. A total of 100 patients, all with a history of secondary cesarean section, were selected as research subjects for this experimental study. The selected patients were divided into two groups: the experimental group, who received a diagnosis through hysteroscopy combined with B-ultrasound diagnosis, and the control group, who underwent vaginal ultrasound diagnosis. Each group comprised 50 patients. The detection of uterine incision diverticula using the two methods was analyzed. Results: The combined diagnostic method of hysteroscopy and B-ultrasound in the experimental group revealed higher length, width, and depth measurements of uterine incision diverticulum defects post-cesarean section compared to the diagnostic method of the control group (P < 0.05), indicating a better diagnostic effect. Conclusion: Upon observing the recovery of patients after cesarean section, the diagnostic method involving hysteroscopy combined with B-ultrasound yielded superior results. This method enhances diagnostic accuracy and enables the identification of patients’ incisional diverticulum, facilitating proactive intervention. Its significance is noteworthy and merits promotion.

Clinical Efficacy of Microwave Combined with Sophora flavescens Gel in Treating HPV Infection Complicated with Chronic Cervicitis and its Influence on Vaginal Microecology of Patients

Yan Cheng, Jiangzheng Huang — Thu, 13 Jun 2024 00:00:00 +0800

Objective: To analyze the effect of microwave combined with Sophora flavescens gel in patients with HPV infection and chronic cervicitis (CC). Methods: From May 2022 to May 2023, 65 patients with HPV infection complicated with CC were randomly selected and divided into group A (31 cases, microwave) and group B (34 cases, microwave + Sophora flavescens gel) by numerical numbering envelope method, and the effects of the two groups were compared. Results: The positive rate of vaginal microenvironment factors, inflammatory factor indexes, immune function indexes, and HPV-DNA viral load in group B were better than those in group A in the following month after treatment (P < 0.05). Conclusion: Combined use of microwave and Sophora flavescens gel in patients with HPV infection and CC can better improve the vaginal microenvironment and inflammatory reaction, boost the body’s immune function, and reduce HPV-DNA viral load.

Clinical Effect of Warm Acupuncture and Moxibustion Combined with Traditional Chinese Herbs in Treating Cold-Damp Stagnation Dysmenorrhea

Nan Yang — Thu, 13 Jun 2024 00:00:00 +0800

Objective: To investigate the clinical effect of warm acupuncture and moxibustion with traditional Chinese herbs in treating cold-damp stagnation dysmenorrhea. Methods: 76 patients with cold-damp stagnation dysmenorrhea admitted to our hospital were selected as the sample for study and evaluation, and the time of admission to the hospital was from January–December 2023. The patients were divided into an observation group (n = 38) and a control group (n = 38) using a random number table. The patients in the control group were treated with conventional Western analgesic drugs. In contrast, the patients in the observation group were treated with warm acupuncture and moxibustion together with traditional Chinese herbs. The clinical effective rate, traditional Chinese medicine (TCM) symptom score, NRS score, serum factor level, and the incidence rate of adverse reactions were compared between the two groups. Results: The clinical efficacy of the observation group was higher than that of the control group (P < 0.05); the TCM symptom score of the observation group was lower than that of the control group (P < 0.05); the PGF2a and NRS scores of the observation group were lower than that of the control group, while the PGE2 was higher than that of the control group (P < 0.05); the incidence rate of adverse reactions of the observation group was lower than that of the control group (P＜0.05). Conclusion: Warm acupuncture and moxibustion combined with traditional Chinese herbs are effective in treating patients with cold-damp stagnation dysmenorrhea. This treatment regime alleviates clinical symptoms, reduces the degree of pain, improves the level of serum factor, and reduces the incidence of adverse reactions. Therefore, it should be popularized.

Analysis of the Clinical Effect of Multi-Drug Combination Therapy on Patients with Gynecological Inflammation

Fei Gao — Thu, 13 Jun 2024 00:00:00 +0800

Objective: To investigate the effect of multi-drug combination therapy for patients diagnosed with gynecological inflammation. Methods: A total of 100 patients diagnosed with gynecological inflammation between August 2023 and January 2024 were selected as the study subjects. The patients were separated into a control group and an observation group, with 50 patients in each group. The control group underwent conventional drug therapy while the observation group combined lactobacillus vaginal capsule treatment. The clinical effects of the treatments were compared. Results: The total efficacy of the treatment received in the observation was higher. The time taken for gynecological symptom relief was shorter, and the values of vaginal pH, interleukin-6 (IL-6), and C-reactive protein (CRP) were lower after treatment (P < 0.05) compared to the control group. Conclusion: The multi-drug combination therapy can achieve rapid symptomatic relief and improve the vaginal microenvironment in patients with gynecological inflammation, which can reduce their inflammatory response and improve their prognosis.

Clinical Efficacy Analysis of Different Surgical Modalities in the Treatment of Endometrial Polyps Under Hysteroscopy

Yan Yu, Lingna Sun, Yongjie Tian — Thu, 13 Jun 2024 15:49:30 +0800

Objective: To investigate the clinical effects of hysteroscopic electrosurgery and hysteroscopic diagnostic scraping on the treatment of endometrial polyps. Methods: Clinical data from 128 patients with endometrial polyps included in the study were collected and randomly divided into two groups, with 64 cases each in the electrodesiccation group and diagnostic scraping group. The electrodesiccation group underwent hysteroscopic electrodesiccation, while the diagnostic scraping group underwent hysteroscopic diagnostic scraping. Clinical indicators were combined to compare the efficacy of the two groups. Results: (1) Following treatment, the hemoglobin level in the electrodesiccation group was significantly higher than that in the diagnostic curettage group, and the endometrial thickness was significantly lower than that in the diagnostic curettage group (P < 0.001); (2) After treatment, the serum VEGF level in the electrodesiccation group was significantly lower than that in the diagnostic curettage group (P < 0.001); (3) Operative time and operative bleeding in the electrodesiccation group were significantly lower than those in the diagnostic scraping group (P < 0.001); (4) The complication rate was significantly lower in the electrodesiccation group (4, 6.251%) compared to the diagnostic scraping group (12, 18.751%), with a P value less than 0.05 (P = 0.033). Conclusion: Hysteroscopic electrosurgery demonstrates superior efficacy in the treatment of endometrial polyps compared to hysteroscopic curettage.

Analysis of the Effect of Maternal Serologic Prenatal Screening in Mid-Trimester Pregnancy

Yujie Lv, Qiuzhi Yu, Hong Quan — Thu, 13 Jun 2024 16:03:30 +0800

Objective: To analyze the results of maternal serological prenatal screening in the middle trimester. Methods: The study was conducted on 7815 middle-pregnant women who underwent prenatal screening in our hospital between January 2021 and December 2022, of which pregnant women aged 35 years and above were taken as the high-age group; those who were under 35 years old were included in the low-age group. The results of maternal serological screening in mid-pregnancy were analyzed. Results: The probability of detecting the disease was higher in prenatal screening results. Conclusion: Maternal serologic prenatal screening in the middle trimester has the advantages of economy and convenience, and can effectively reduce birth defects in newborns, which is of some value for promotion.

Comparison of Clinical Effects Between Minimally Invasive Laparoscopic Surgery and Laparotomy in Treating Ovarian Endometriosis Cysts

Yao Yao — Thu, 13 Jun 2024 16:18:48 +0800

Objective: To compare the clinical effects of laparoscopic minimally invasive surgery and laparotomy in the treatment of ovarian endometriosis cysts. Methods: 66 patients with endometriosis cysts admitted to our hospital from December 2022 to December 2023 were selected as the study subjects and randomly divided into a control group (n = 33) and an observation group (n = 33). The control group was treated with laparotomy, and the observation group was treated with minimally invasive laparoscopic surgery. The surgical indexes, ovarian function indexes, and complications were observed. Results: All surgical indexes of the observation group (surgical time, intraoperative blood volume, hospital stay, postoperative antibiotic use time) were significantly better than the control group, (P_mean< 0.001). After surgery, the E₂ score of ovarian function indexes in the observation group was higher than that in the control group, while the luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels were lower than those in the control (t = 5.246, t = 5.173, t = 3.535, P_mean< 0.001). Lastly, the overall incidence of complications in the observation group (1/3.03%) was lower than that in the control group (8/24.24%), (χ²= 4.632, P < 0.05). Conclusion: Minimally invasive laparoscopic surgery is more effective than laparotomy in treating ovarian endometriosis.

Significance of Mid-Pregnancy Down Syndrome Risk Screening in Predicting Adverse Maternal and Fetal Outcomes

Qiuzhi Yu, Hong Quan, Yujie Lv — Thu, 13 Jun 2024 16:28:59 +0800

Objective: To investigate the value of mid-pregnancy Down syndrome risk screening in predicting adverse maternal and fetal outcomes. Methods: 536 mothers who underwent mid-pregnancy screening for Down syndrome at Chengyang District Maternal and Child Healthcare and Family Planning Service Center from January 2021 to December 2022 were selected for retrospective analysis. The risk was calculated using the Asian population database in the American prenatal screening software PRISCA 4.0, combined with the age, gestational week, and body mass of the day of the pregnant women's blood collection. Results: The screening results showed that there were 469, 54, and 13 cases in the low-risk, critical-risk, and high-risk groups, respectively, and there were no statistically significant differences in the age and body mass of each group (P > 0.05). However, there was a significant difference between the adverse fetal outcomes in low-risk, critical-risk, and high-risk groups (P < 0.05); and the screening results showed that there was a significant difference between the adverse maternal outcomes in the low-risk, critical-risk, and high-risk groups (P < 0.05). Conclusion: There is a relationship between the high risk of Down syndrome detected through screening and adverse maternal and fetal outcomes. Besides, the false positive and negative rates of Down syndrome screening results are positively correlated with adverse maternal and fetal outcomes.

Analysis of the Relationship Between Body Perception and Self-Esteem of Women with Total Abdominal Hysterectomy Bilateral Salpingo-Oophorectomy Surgery – A Secondary Publication

Ahu Aksoy Can, Aysu Buldum, Filiz Değirmenci, Duygu Vefikuluçay Yılmaz — Thu, 13 Jun 2024 16:48:01 +0800

Objective: To determine the relationship between body image and self-esteem of women who underwent total abdominal hysterectomy bilateral salpingo-oophorectomy (TAH-BSO). Method: The sample of the descriptive study consisted of 118 women who underwent TAH-BSO in the obstetrics and gynecology service of a university hospital in Mersin. Data was collected using a self-made questionnaire, the Body Perception Scale (BAS), and the Rosenberg Self-Esteem Scale (RBSS). Descriptive statistics included median, mean, standard deviation, number, and percentage values. Data evaluation methods included Mann-Whitney U Test and t-test to compare the means of two groups; Kruskal Wallis test and one-way ANOVA were used to compare the means of more than two groups; and Spearman correlation coefficient was used to determine the relationship between two continuous variables. Results: The mean age of the women was 50.13 ± 9.57, and the mean duration of marriage was 26.53 ± 11.97 years. It was found that 86.4% of the women were married, 40.7% were primary school graduates, and 55.1% had at least three children. Besides, 47.5% of the women applied to the hospital with the complaint of bleeding and according to 39% of them, the uterus meant nothing to them. Furthermore, the mean score of the women in BAI was 151.05 ± 26.64, and the mean score from RBSS was 5.02 ± 1.08. In the study, it was found that there was no statistically significant relationship between BAI and RBRS (r = -0.113; P = 0.224). Conclusion: In this study, it was determined that TAH-BSO surgery did not have a negative effect on women’s body perceptions and self-esteem. This result shows that women’s perspectives on common gynecological surgeries such as TAH-BSO have changed.

Analysis of the Impact of Standardized Patient Teaching Model on Clinical Practice Results in Obstetrics and Gynecology

Qun Dang, Lili Zhang — Thu, 13 Jun 2024 17:37:17 +0800

Objective: To explore the effect of the standardized patient teaching model on the clinical practice of obstetrics and gynecology. Methods: Interns of the hospital’s Department of Obstetrics and Gynecology that were from the May 2022 to July 2023 batch were selected as the study subjects. A total of 42 people were selected, and they were separated into a traditional group and an observation group using a random number table method, with 21 people in each group. The former group underwent traditional teaching while the latter underwent standardized patient teaching. Results: The scores of interns in the observation group for theoretical knowledge, case analysis, and clinical practice were all significantly higher than those of the traditional group (P < 0.01). Besides, the interns in the observation group gave higher scores for teaching content, teaching methods, and teacher satisfaction than those of the traditional group (P < 0.01). Conclusion: The standardized patient teaching model is conducive to improving interns’ professional skills and increasing their teaching satisfaction, so it should be popularized.

Analysis of the Feasibility of Different Surgical Methods for Treating Uterine Fibroids and Their Impact on the Ovarian Function

Mei Jiang — Thu, 13 Jun 2024 00:00:00 +0800

Objective: To analyze the feasibility of different surgical methods for treating uterine fibroids and their impact on ovarian function. Methods: 90 patients with uterine fibroids admitted to our hospital from December 2018 to April 2023 were divided into Group A and Group B, with 45 patients in each group. Group A underwent laparoscopic myomectomy (LM) and Group B underwent transcervical resection of myoma (TCRM). The patients were followed up 3 months after surgery and their clinical indexes were compared. Results: The duration of hospitalization, surgery, anal ventilation, and getting out of bed were shorter in Group B. Besides, Group B also experience less intraoperative bleeding (P < 0.05). There was no difference in the follicle-stimulating hormone (FSH), luteinizing hormone LH, estradiol (E2), and anta follicle count (AFC) levels between the two groups after surgery (P > 0.05). The Female Sexual Function Index scores of two groups increased significantly after surgery, with Group B showing a more drastic increase (P < 0.05); The VAS ratings of the two groups showed a decreasing trend 1–5 days after surgery, with Group B showing a larger decrease (P < 0.05). There was no difference in the incidence of complications between the two groups within 3 months after surgery (P > 0.05). Conclusion: Both LM and TCRM are effective in treating uterine fibroids with little impact on ovarian function and complications. However, TCRM is associated with reduced bleeding, quicker postoperative recovery, decreased pain, and an enhanced quality of sexual life. Therefore, this surgical approach appears more beneficial for improving prognosis.

Analysis of the Effect of Danshen Polyphenols Combined with Doxofylline in Treating Chronic Pulmonary Heart Disease Patients in the Compensated Stage

Fen Yang, Meijuan Ma — Thu, 13 Jun 2024 00:00:00 +0800

Objective: To analyze the effect of Danshen polyphenols combined with doxofylline treatment in patients with chronic pulmonary heart disease in the compensated stage. Methods: 76 patients with chronic pulmonary heart disease in the compensated stage were selected from January 2023 to January 2024 as the study subjects, and they were divided into a study group and a reference group through a random number table. the study group was treated with Danshen polyphenols combined with doxorubicin while the reference group was treated with conventional treatment, and the treatment effects of the two groups were compared. Results: The patients in the study group were treated with Danshen polyphenols combined with doxorubicin, and the maximal ventilation was 73.26 ± 4.83 L/min, the left ventricular ejection fraction was 56.14 ± 1.98 %, and the total effective rate of the treatment was 94.74%, which were all significantly better than those of the reference group (P < 0.05), which is statistically significant. Conclusion: Danshen polyphenols combined with doxofylline treatment resulted in an improvement in maximum ventilation and left ventricular ejection fraction, and its overall efficacy is also higher than conventional treatment in treating chronic pulmonary heart disease in the compensated stage.

The Effect of Assisted Reproductive Technology on Morbidity and Mortality of Twin Premature — A Secondary Publication

Burak Ceran, Ufuk Çakir, Ali Ulaş Tuğcu, Cüneyt Tayman — Thu, 13 Jun 2024 00:00:00 +0800

Objective: It is thought that twin neonates born from pregnancies resulting from assisted reproductive technology (ART) are clinically riskier than twin neonates born from spontaneous pregnancy. However, information on the risks in premature infants born as a result of ART pregnancies is limited. In our study, premature twin infants born from ART and spontaneous pregnancies were compared to clinical outcomes. Method: All premature twin infants hospitalized in our unit between September 2017 and September 2019 and born under 32 weeks of gestation were included in our study. Demographic and clinical results of premature twins born as a result of spontaneous and ART pregnancies were compared. Results: A total of 142 premature twins, 116 (81.6%) in the spontaneous twin group and 26 (18.4%) in the ART twin group, were included in the study. Demographic and clinical features were similar between ART and spontaneous twin groups (P > 0.05). Conclusion: Our study determined that premature infants born due to ART pregnancies did not have any additional risk compared to spontaneous infants. This result shows that the main determinants of clinical outcomes in premature infants are gestational week and birth weight.