Advances in Obstetrics and Gynecology Research

Clinical Value of Insulin Aspartate Injection In The Treatment of Obstetric Gestational Diabetes Mellitus

Yuliang Zhang — 2025-01-06

Gestational diabetes mellitus (GDM) is a common metabolic disorder during pregnancy, which has a high incidence and has a serious impact on maternal and infant health, including premature delivery, macrosomia and postpartum complications. Therefore, timely and effective treatment is particularly important. The purpose of this study was to investigate the clinical value of insulin aspartate in the management of gestational diabetes mellitus, and to provide evidence for improving the treatment of gestational diabetes mellitus. Through the comprehensive analysis of the pharmacological properties and clinical applications of insulin aspartate, the research results showed that insulin aspartate can effectively control blood sugar levels and reduce adverse pregnancy outcomes in the treatment of gestational diabetes mellitus. It is worth noting that during the use of insulin aspartate, the impact on the mother and child is relatively small, and does not affect breastfeeding, reflecting its importance in the treatment of gestational diabetes. To provide a new treatment idea for the clinical management of gestational diabetes mellitus, emphasize the importance of individualized treatment, and lay a foundation for future related research.

Demographic and Clinical Characteristics of Breast Cancer Patients in Bahawalpur Pakistan: A Comprehensive Analysis

Mehran Khan — 2025-01-03

This study was conducted at Bahawalpur Medical and Dental College (BMDC) in collaboration with Bahawalpur Institute of Nuclear Oncology (BINO) Hospital, Pakistan, and aimed to analyze the demographic and clinical characteristics of breast cancer patients. A self-structured questionnaire was developed to collect comprehensive data, including gender, age, regional residence, marital status, reproductive history, BMI, cancer type, stage, time of detection, and family cancer history. Data were collected from 500 female breast cancer patients, with 402 meeting inclusion criteria after excluding incomplete records and male patients. The study revealed a distribution of breast cancer cases across age groups, with a majority aged 41–60 years. BMI classification showed notable proportions of patients classified as obese. Family cancer history was reported in 35.3% of patients. Most patients were non-smokers (97%), and reproductive status showed 37.3% premenopausal, 60.2% postmenopausal, and 2.5% nulliparous. Cancer staging indicated 7.9% with stage 1, 27.4% with stage 2, 42.0% with stage 3, and 16.2% with stage 4 cancer. The majority (95.3%) were diagnosed within 0–5 years of detection. Comparisons with existing literature highlight consistency in age distribution trends and BMI correlations, while variations exist in family cancer history and smoking prevalence. The findings emphasize the importance of tailored prevention and early detection strategies, considering demographic and clinical profiles to enhance breast cancer management and outcomes in Bahawalpur, Pakistan. Further research is warranted to validate these findings and explore additional factors influencing breast cancer incidence and treatment responses.

Study on the Clinical Significance and Expression Level of CA-125 and D-dimer in the Serum of Patients with Adenomyosis

Narankhuu Ijilmurun — 2025-01-03

CA-125 and D-dimer show potential applications in diagnosing and managing adenomyosis. As a traditional tumor marker, CA-125 may show a trend of increase in patients with adenomyosis, but its specificity is insufficient, because it may also increase in various gynecological diseases. As a measure of coagulation activity, D-dimer may be associated with inflammation and tissue changes related to adenomyosis. However, its specific mechanism of action and diagnostic efficacy still need to be further studied. Current studies are limited by the small sample size, insufficient standardization and lack of dynamic monitoring data, these factors limit the general applicability of the conclusions and practical value of the application. Therefore, it is particularly urgent to conduct large-scale, prospective studies to verify the effectiveness of these biomarkers and to explore their combined application in the diagnosis and management of adenomyosis. This will help to develop more accurate diagnosis and treatment plans and enhance the scientificity of clinical decision-making.

Research on the Demand for Postpartum Health Management and its Influencing Factors in Yulin

Qiwen Li — 2025-01-07

This study investigated mothers’ postpartum health management needs in Yulin City to study ways to improve maternal health management services. An electronic questionnaire survey was conducted on the postpartum follow-up of women in the First People’s Hospital of Yulin City, the Red Cross Hospital of Yulin City and the postpartum outpatient clinic of Guinan Hospital of Yulin City. The overall score of postpartum health management needs of the surveyed mothers was (4.34 ± 0.53) points. The average score of the required items was from high to low, which were (4.42 ± 0.56) points in the dimension of neonatal care needs, (4.33 ± 0.68) points in the dimensions of social support needs, and (4.27 ± 0.59) points in the dimensions of maternal physical and mental recovery needs. The main factors influencing the need for postpartum health management were education level, delivery experience, pregnancy complications/complications, and postpartum sleep (P < 0.05).