Tong, Zhongsheng, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin 300000, China;Tianjin’s Clinical Research Center for Cancer, Tianjin 300000, China;Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China;Key Laboratory of Cancer Prevention and Therapy, Tianjin 300000, China, China