Abstract
Lung cancer is the leading cause of cancer-related mortality in both men and women, and lung adenocarcinoma accounts for approximately 75-85% of all lung cancers. It is expected to cause 10 million deaths per year worldwide by the year 2030. A large number of lung cancers are associated with cigarette smoke, although other factors such as environmental influences and radon or nutrition may also be involved. Lung adenocarcinoma commonly develops resistance to radiation and chemotherapy, and often presents at stages too late for surgical intervention. The present review discuss about the epidemiology, etiology, pathogenesis, and chemoprevention of lung cancer.