Assessing the Clinical Efficacy and Effectiveness of Sentinel Lymph Node Biopsy Combined with Breast-Conserving Surgery for Early-Stage Breast Cancer
Download PDF

Keywords

Early breast cancer
Sentinel lymph node biopsy
Breast-conserving surgery
Clinical efficacy

DOI

10.26689/par.v7i6.5649

Submitted : 2023-10-23
Accepted : 2023-11-07
Published : 2023-11-22

Abstract

Objective: To analyze the impact of sentinel lymph node biopsy (SLNB) combined with breast-conserving surgery in the clinical treatment of early-stage breast cancer. Methods: 80 patients with early-stage breast cancer admitted to the Second Department of Breast Surgery at Dezhou Second People’s Hospital from September 2020 to September 2022 were selected and randomly divided into a control group and an observation group using the random number table method, with 40 cases in each group. The control group underwent a modified radical mastectomy, while the observation group underwent SLNB combined with breast-conserving surgery. The surgical efficacy and prognosis between the two groups were compared. Results: The observation group exhibited shorter operation, hospitalization, and extubation times, as well as less intraoperative blood loss and drainage volume, all of which were significantly better than those in the control group (P < 0.05). Additionally, the observation group demonstrated a higher rate of excellent breast cosmetology and quality of life, with lower complication incidence, significantly outperforming the control group (P < 0.05). There was no statistical difference in the metastasis rate and recurrence rate between the two groups (P > 0.05). Conclusion: The combination of SLNB and breast-conserving surgery proves highly effective for patients with early-stage breast cancer, presenting fewer complications and enhancing both breast cosmetic outcomes and quality of life.

References

Xie Y, Dong Y, Song H, et al., 2020, Application Value of Breast Conservation Combined with Sentinel Lymph Node Biopsy Surgery and Modified Radical Mastectomy in the Treatment of Early Breast Cancer. Chinese Journal of Clinical Oncology and Rehabilitation, 27(7): 856–860.

Wang C, Li X, Wen J, et al., 2020, Effects of Breast-Conserving Surgery Combined with Sentinel Lymph Node Biopsy on Axillary Extubation Time, Shoulder Joint Mobility and Long-Term Efficacy in Patients with Early Breast Cancer. China Medical Herald, 17(36): 105–109.

Liu P, Zhang H, Li W, et al., 2020, Observation on the Effect of Breast-Conserving Surgery Combined with Sentinel Lymph Node Biopsy in the Treatment of Early Breast Cancer. Chinese Journal of Practical Medicine, 47(22): 69–71.

Shen J, Bao X, Ma Y, et al., 2021, Observation on the Clinical Efficacy of Sentinel Lymph Node Biopsy Combined with Breast-Conserving Surgery and Radical Resection in the Treatment of Breast Cancer. Shanxi Medical Journal, 50(3): 433–435.

Fang W, Zong S, Zhang C, et al., 2022, Clinical Study of Breast-Conserving Surgery Combined with Sentinel Lymph Node Biopsy in the Treatment of Early Triple-Negative Breast Cancer. Progress in Modern General Surgery in China, 25(8): 636–638.

Yang H, Feng X, Chen Y, et al., 2022, Effect of Breast-Conserving Surgery Combined with Sentinel Lymph Node Biopsy on Prognosis and Breast Cosmetic Satisfaction in Patients with Early Breast Cancer. Cancer Progress, 20(24): 2557–2559 + 2563.

Zheng S, Cao C, 2022, The Efficacy of Breast Conservation Combined with Sentinel Lymph Node Biopsy in the Treatment of Early Triple-Negative Breast Cancer and Its Impact on Postoperative Quality of Life. Chinese Maternal and Child Health Care, 37(1): 48–51.

Song D, 2019, Research on the Clinical Application Value of Sentinel Lymph Node Biopsy in Breast-Conserving Treatment of Early Breast Cancer. Heilongjiang Traditional Chinese Medicine, 48(1): 217–218.

Yu X, 2021, Clinical Efficacy of Breast Conservation Combined with Sentinel Lymph Node Biopsy in Patients with Early Breast Cancer. Chinese Practical Medicine, 16(28): 34–37.

Wu G, Zhong M, Zhang B, et al., 2020, Research on the Application of Sentinel Lymph Node Biopsy Combined with Breast-Conserving and Axillary-Conserving Surgery in the Treatment of Early Breast Cancer. Modern Chinese Doctors, 2020(36): 57–61.