A Discussion on TCM Treatment and the Pathogenesis of Membranous Nephropathy in Primary Nephrotic Syndrome
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Keywords

Primary nephrotic syndrome
Membranous nephropathy
Traditional Chinese medicine
Qidi Gushen prescription
Pathogenesis

DOI

10.26689/par.v6i4.4173

Abstract

Objective: To investigate the TCM treatment principle of membranous nephropathy and its effect. Methods: A total of 56 patients were selected from the Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine. They were then divided into the control group (western medicine standard therapy) and the study group (Qidi Gushen prescription), with 28 patients in each group. The treatment effect, treatment safety, and patients’ satisfaction were observed and compared between the two groups. Results: The results showed that the treatment effect of the study group was 96.43%, which was significantly better compared with the control group (75.00%) (p < 0.05); in terms of safety, the probability of adverse events was 7.14% in the study group and 32.14% in the control group, in which the difference was statistically significant (p < 0.05); in addition, the study group’s satisfaction with the treatment measures was significantly higher than that of the control group (p < 0.05). Conclusion: In treating membranous nephropathy, traditional Chinese medicine can be tailored to its pathogenesis, which is not only beneficial to the treatment effect, but also has a high safety profile.

References

Qin C, 2018, Discussion on TCM Treatment and Pathogenesis of Membranous Nephropathy in Primary Nephrotic Syndrome. Special Health, 2018(22): 45.

Lei G, 2016, Discussion on TCM Pathogenesis and Treatment of Membranous Nephropathy in Primary Nephrotic Syndrome. Chinese Journal of Integrated Traditional and Western Medicine Nephropathy, 17(5): 443–445.

Pan Q, Ye Z, Zeng C, et al., 2020, Comparison of Clinical Characteristics Between Idiopathic Membranous Nephropathy and Four Common Nephropathy. Chinese Journal of Clinical New Medicine, 13(4): 4.

Gao Y, Cai C, Wang S, 2020, Therapeutic Effect of Yishen Huashi Granule on Nephrotic Syndrome Patients with Idiopathic Membranous Nephropathy. Heilongjiang Traditional Chinese Medicine, 2020(3): 33–34.

Cai X, Zhang X, Zhong Y, et al., 2020, Correlation Between Clinicopathological Features and Renal Function in Patients with Idiopathic Membranous Nephropathy with Nephrotic Syndrome. Chinese Journal of Integrated Traditional and Western Medicine Nephropathy, 21(4): 317–320.

Zheng J, Yang L, Zhang L, et al., 2022, Expert Investigation, Analysis and Discussion on Common TCM Syndrome Types of Primary Membranous Nephropathy. Introduction to Traditional Chinese Medicine, 28(2): 113–117.

Chang M, Zhang Y, 2021, Treatment of Membranous Nephropathy with Traditional Chinese Medicine. World Journal of Integrated Traditional Chinese and Western Medicine, 16(6): 1173–1176.

Pan Y, Wang K, Dai C, et al., 2020, Chenzhiqiang’s Experience in Treating Idiopathic Membranous Nephropathy with Traditional Chinese Medicine. Chinese Journal of Traditional Chinese Medicine, 35(7): 3460–3462.

Li Q, Ren R, Li Z, et al., 2021, Zhaoyuyong’s Experience in Treating Membranous Nephropathy. Jiangsu Journal of Traditional Chinese Medicine, 53(8): 20–22.

Tong M, 2021, Progress in Diagnosis and Treatment of Primary Membranous Nephropathy. Zhejiang Medical Journal, 43(4): 352–357.

Li F, 2021, Comparative Study on Clinical Efficacy of Different Treatment Schemes for Membranous Nephropathy. Chinese Journal of Nephrology with Integrated Traditional and Western Medicine, 22(7): 635–637.

Dong Z, Dai H, Miao W, et al., 2021, Analysis of Clinical Experience in Treating Idiopathic Membranous Nephropathy by Warming Yang and Resolving Exterior Syndrome. Beijing Traditional Chinese Medicine, 40(2): 113–116.

Luan Z, Dai H, Miao W, et al., 2019, Discussion on TCM Pathogenesis and Treatment of Membranous Nephropathy in Primary Nephrotic Syndrome. Diet Science, 2019(12): 58.

Gao H, 2018, Progress in TCM Treatment of Intractable Nephrotic Syndrome. Health Care Guide, 000(020): 271.

Teng J, Huang F, Meng G, 2019, Curative Effect of Traditional Chinese Medicine on Membranous Nephropathy of Primary Nephrotic Syndrome. China Health Standard Management, 10(9): 99–101.