Objective: To analyze the clinical effect of pegaspargase combined with chemotherapy on patients with lymphoma. Methods: Seventy patients with lymphoma admitted to Shaanxi Provincial People’s Hospital between December 2020 and June 2021 were selected as study subjects and were equally divided into the control group and the intervention group using the lottery method, with 35 cases in each group; the control group received conventional treatment, while the intervention group received pegaspargase combined with chemotherapy. The treatment satisfaction, quality of life, psychological status, and incidence of adverse reactions of the patients in the two groups were compared. Results: The differences in the indicators between the two groups were statistically significant (p < 0.05). Conclusion: Pegaspargase combined with chemotherapy can effectively improve the treatment effect and satisfaction of lymphoma patients; hence, it is worthy of promotion in clinical treatment.
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