Research Progress of the Maternal-Fetal Interface Immune Microenvironment Regulated by Traditional Chinese Medicine in the Treatment of Recurrent Spontaneous Abortion
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Keywords

Maternal-fetal interface
Immune microenvironment
Traditional Chinese medicine
Research progress

DOI

10.26689/par.v5i6.2784

Submitted : 2021-10-31
Accepted : 2021-11-15
Published : 2021-11-30

Abstract

This article is a summary of the research progress of the maternal-fetal interface immune microenvironment regulated by traditional Chinese medicine in the treatment of recurrent spontaneous abortion. The imbalance of the immune microenvironment at the maternal-fetal interface is closely related to the occurrence of recurrent spontaneous abortion. Traditional Chinese medicine can maintain the homeostasis of the immune microenvironment at the maternal-fetal interface by regulating the function of immune cells and the expression of related cytokines.

References

Zhang J, 2016, Expert Consensus on the Diagnosis and Treatment of Recurrent Abortion. Chinese Journal of Obstetrics and Gynecology, 51(01): 3-9.

Saravelos SH, Regan L, 2014, Unexplained Recurrent Pregnancy Loss. Obstet Gynecol Clin North Am, 41(1): 157-166.

LiX, Zhou J, Fang M, et al., 2020, Pregnancy Immune Tolerance at the Maternal-Fetal Interface. International Reviews of Immunology, (2): 1-17.

Turco MY, Moffett A, 2019, Development of the Human Placenta. Development, 146(22): dev163428.

Bulmer JN, Williams PJ, Lash GE, 2010, Immune Cells in the Placental Bed. Int J Dev Biol, 54(2-3): 281-294.

Liu S, Diao L, Huang C, et al., 2017, The Role of Decidual Immune Cells on Human Pregnancy. J Reprod Immunol, 124: 44-53.

Kieffer TEC, Laskewitz A, Scherjon SA, et al., 2019, Memory T Cells in Pregnancy. Front Immunol, 2(10): 625.

Weiping C, 2018, Study on the Effect and Mechanism of Kidney-Supplementing Thoroughfare-Securing Method on Regulating NK Cell Function and Subgroup Differentiation in the Treatment of URSA with Kidney Deficiency. Shandong University of Traditional Chinese Medicine.

Sun J, Yang Z, Guo T, 2017, Intervention Effect of Taishan Panshi Powder on Immune Cell Function of Maternal-Fetal Interface in Mice with Repeated Spontaneous Abortion. Chinese Archives of Traditional Chinese Medicine, 035(010): 2689-2692.

Zuo X, 2019, Analysis of Medication Rules in the Treatment of Recurrent Abortion with Traditional Chinese Medicine and Study on the Influence of Treg/Th17 Balance Mechanism. Zhejiang Chinese Medical University.