Objective: To analyze the application value of MRI and CT diagnosis for those with lumbar disc herniation. Methods: The data of 62 patients with LDH treated in our hospital from January 2019 to December 2019 were analyzed retrospectively. All patients were diagnosed as LDH after operation, and 62 patients were treated with MRI and CT. The accuracy of CT and MRI in the diagnosis was analyzed according to the gold standard of operation results. Results: 62 patients were diagnosed as LDH after operation, including 25 cases with intervertebral disc herniation, 12 cases with intervertebral disc prolapse, 8 cases with intervertebral disc nodule, 7 cases with intervertebral disc dissociation as well as 10 cases with intervertebral disc bulge. The accuracy of MRI diagnosis (95.16%) was higher than that of CT (75.81%), and the difference was statistically significant (P<0.05). Conclusion: For the diagnosis of LDH, MRI is more accurate, but CT is faster and cheaper. Both of them have their own advantages and can be chosen clinically according to the actual situation of patients on the basis of ensuring the diagnostic accuracy.