Journal of Clinical and Nursing Research

Effects of Continuous Precision Nursing Model on Knowledge, Attitudes, and Practices (KAP) Behavior and Cardiac Function in Patients after Percutaneous Coronary Angiography and Stent Implantation

Cuiying Han — Thu, 14 Mar 2024 00:00:00 +0800

Objective: To explore the impact of a continuous precision nursing model on patients’ Knowledge, Attitudes, and Practices (KAP) and cardiac function during the nursing process of patients undergoing percutaneous coronary angiography and stent implantation. Methods: Ninety patients who underwent percutaneous coronary angiography and stent implantation in our hospital from April 2022 to April 2023 were selected and randomly divided into the control group (45 cases), in which routine nursing support was carried out during the treatment process, and the observation group (45 cases), in which continuous precision nursing model was carried out during the treatment process. Comparisons were made between the two groups of patients on their KAP, cardiac function, and quality of life during recovery. Results: There was no difference in the left ventricular ejection fraction (LVEF), cardiac output (CO), and cardiac index (CI) levels before intervention. After the intervention, the levels of cardiac function in the observation group were higher than those of the control group (P < 0.05). There was no difference in the Exercise of Self-Care Agency (ESCA) self-care ability scale scores before the intervention. After the intervention, the observation group had higher ESCA scores than the control group (P < 0.05). Conclusion: Implementation of a continuous precision nursing model in the care of patients undergoing percutaneous coronary angiography and stent implantation improved the patient’s cardiac function, and KAP, and promoted recovery.

Analysis of the Significance of Key Points of Patient Interventional Psychological Care and Pain Care

Xiaoping Dai, Chu Luo, Jiawei Dai — Sun, 24 Mar 2024 00:00:00 +0800

Interventional therapy has become increasingly popular in clinical practice due to advancements in medical technology. However, patients often experience psychological and physiological pressure due to its invasive nature. The management of patient discomfort and tension is crucial to ensure effective treatment. Psychological and pain management are essential components of interventional therapy, as they significantly impact patient recovery and prognosis. This article discussed the importance of interventional psychological and pain care for patients, starting with the development and spread of interventional therapy. The significance of providing high-quality nursing services to patients and improving their quality of life was also discussed.

Analysis of Imaging Characteristics and Dynamic Changes of 3 Cases of Severe Novel Coronavirus Pneumonia in Qinghai Province

Yingfang Yu, Ruiyun Zhao, Changde Li, Fuqiang Ma, Lingyun Guo, Yang Li — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To analyze the characteristics, dynamic changes, and outcomes of the first imaging manifestations of 3 patients with severe COVID-19 in our hospital. Methods: Computed tomography (CT) findings of 3 patients with severe COVID-19 who tested positive by the nucleic acid test in our hospital were selected, mainly focusing on the morphology, distribution characteristics, and dynamic changes of the first CT findings. Results: 3 patients with severe pneumonia were older, with one aged 80. The first chest CT examination for all 3 patients differed. Imaging showed a leafy distribution of consolidation, primarily affecting the lower lobes of both lungs and extending subpleurally. A grid-like pattern was observed, along with changes in the consolidation and air bronchogram. These changes had slower absorption, especially in patients with underlying diseases. Conclusion: CT manifestations of severe COVID-19 have specific characteristics and the analysis of their characteristics and dynamic changes provide valuable insights for clinical treatment.

Progress in The Application of Nursing Care Based on ERAS Concept after Thoracolumbar Fracture Surgery

Ruigang Zhu, Limiao Cui, Rui Zhou — Sun, 24 Mar 2024 00:00:00 +0800

Thoracic spine fracture is a common orthopedic injury that is usually caused by external forces acting directly on or transmitted to the thoracic spine through other parts of the spine. Thoracic spine fractures can be divided into two types: stable and unstable. An unstable fracture means that the relationship between the vertebral bodies is no longer stable, which may cause serious consequences such as spinal compression, nerve root compression, or spinal cord injury. Surgical treatment is often needed for patients with unstable fractures, nerve root compression, or spinal cord injury to restore stability and function to the thoracic spine. The probability of complications after thoracolumbar fracture surgery is high, which affects the outcome of surgical treatment. To improve postoperative rehabilitation outcomes, this article analyzed the value of nursing care based on the enhanced recovery after surgery (ERAS) concept for patients undergoing thoracolumbar fracture surgery.

Investigation of the Clinical Diagnostic Significance of the T-Cell Test for Tuberculosis combined with Erythrocyte Sedimentation Test in Pulmonary Tuberculosis

Jialong Wang — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To investigate the clinical diagnostic significance of peripheral blood T-cell test (T-spot test) for tuberculosis (TB) infection combined with erythrocyte sedimentation rate (ESR) in pulmonary TB. Methods: 41 patients with a clinical diagnosis of TB during hospitalization from January 2020 to April 2023 in our hospital were selected as the experimental group, and 45 patients without TB (bronchopneumonia patients) were selected as the control group. The diagnostic specificity, sensitivity, and accuracy of the T-spot TB test, ESR test, and the combined test of the two were calculated respectively. Results: The sensitivity, specificity, and accuracy of the T-spot TB test combined with ESR for the diagnosis of TB in the experimental group were significantly higher than the individual results of the T-spot TB test and ESR test alone (P < 0.05). Conclusion: The T-spot TB test combined with the ESR test for TB diagnosis has greater clinical value than carrying out the tests individually.

Research Progress on the Application of Cluster Nursing Mode in ECMO-Assisted Patients

Ling Liu, Sheilla Magbanua Trajera — Sun, 24 Mar 2024 00:00:00 +0800

Cluster care, also known as cluster therapy, cluster intervention, or bundled therapy, is a series of evidence- based supportive joint care measures developed to improve the quality of care for specific patients or nursing issues. It is highly reliable and can effectively improve patient prognosis. This article summarized the application of cluster nursing care in extracorporeal membrane oxygenation (ECMO)-assisted patients and the problems faced to provide a reference for evidence-based decision-making in clinical practice.

Analysis of the Application of the Ladder Teaching Method Combined with Case Teaching in Otolaryngology Nursing Teaching

Xiaorong Yang, Shasha Liu, Zhiquan Peng, Ruiqi Li — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To analyze the feasibility of adopting a combined ladder and case teaching method in otolaryngology nursing teaching. Method: Nursing students in the otolaryngology department were selected. According to the admission time of nursing students, 30 nursing students formed a control group (conventional nursing teaching), and 30 nursing students who were admitted later formed an observation group (ladder and case teaching method). The learning performance and teaching effectiveness of nursing students under different teaching methods were analyzed. Result: The academic performance and teaching effectiveness of the observation group were higher than those of the control group (P < 0.05). Conclusion: The implementation of the ladder and case teaching method during the teaching of otolaryngology nursing significantly improved the student’s academic performance and teaching effectiveness. This method has great practical value.

Evaluation of the Efficacy and Effectiveness of Hysteroscopic Electroresection in the Treatment of Submucosal Uterine Fibroids

Guangli Sun — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To evaluate the effect of hysteroscopic electroresection in treating submucosal uterine fibroids. Methods: Using the random number table method, 70 patients with submucosal uterine fibroids were divided into two groups, 35 cases/group. The control group underwent laparoscopic myomectomy, and the observation group underwent hysteroscopic electroresection. Surgical indicators, sex hormone indicators, inflammation indicators, and treatment effects were compared between the two groups. Results: The surgical indicators, sex hormone indicators, and inflammatory indicators three months after operation in the observation group were all more ideal than those of the control group. The total effective rate of the observation group (97.14%) was higher than that of the control group (P < 0.05). Conclusion: Hysteroscopic electroresection for the treatment of submucosal uterine fibroids was less invasive, accelerates recovery, and is more effective.

Application of Mobile Technology and Information Management in Emergency Pre- Examination and Triage

Zhongqing Yang, Ruihua Zhu, Li Shen, Bei Zhu — Sun, 24 Mar 2024 00:00:00 +0800

The primary objective of emergency pre-examination and triage is to provide the most appropriate clinical service to patients with acute and critical illnesses while ensuring the optimal utilization of limited medical resources. With the advancement of medical information technology, mobile technology, and information management, these features have been gradually incorporated into emergency pre-examination and triage and have shown promising outcomes. In this article, the benefits of implementing mobile technology and the current status of integrated information management to provide a reference for the future development and enhancement of emergency pre-examination and triage are reviewed.

Analysis of the Antidepressant Effects and Mechanisms of Icariin II Based on The GABAergic Nervous System

Hongchen Huang, Qinglin Yu, Tong Zhao, Yijian Zhang — Sun, 24 Mar 2024 00:00:00 +0800

This article summarized the research progress on the antidepressant mechanism of icariin II, mainly elaborating on its mechanism from five aspects: GABAergic nervous system, inflammatory response, oxidative stress, neurotrophic factors, and neurotransmitters in the brain. Its clinical application value was further explored to provide a theoretical basis for the development and utilization of icariin II in treating depression.

Comprehensive Rehabilitation Therapy of Traditional Chinese Medicine Combined with Modern Rehabilitation Training Improves the Spasticity and Motor Function of Hemiplegia after Stroke

Yijun Shen — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To analyze the impact of comprehensive rehabilitation therapy of traditional Chinese medicine (TCM) (based on modern rehabilitation training) on the spasticity and motor function in stroke patients with hemiplegia. Methods: Seventy-nine stroke and hemiplegia patients admitted to the hospital from June 2021 to June 2023 were selected and randomly divided into a control group (39 cases) using modern rehabilitation training, and an observation group combined with comprehensive TCM rehabilitation therapy (40 cases), over 1 month. The clinical index data of the two groups were compared. Results: There were differences in the clinical index data between the two groups. The total effective rate after treatment in the observation group (92.50%) was higher than that of the control group (74.36%) (χ² = 4.727, P < 0.05). All central sensitization inventory (CSI) and stroke quality of life (PRO) scores in both groups were lower after treatment, with the observation group having lower scores as compared to the control group (P < 0.05). The scores of FMA (upper limbs, lower limbs), Barthel index scores, and Functional Ambulation Categories (FAC) scores of both groups increased after treatment, with the observation group having higher scores as compared to the control group (P < 0.05). Conclusion: Comprehensive TCM rehabilitation therapy had a significant therapeutic effect on patients with hemiplegia after stroke. It improved the patient’s spasticity, limb movement, and walking function. Their daily living abilities and quality of life were also enhanced.

Analysis of the Effects of Maternal Body Mass Index and Gestational Weight Gain on Maternal and Neonatal Outcomes in Twin Pregnancy

Fanhua Shi, Yuanyuan Li — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To investigate the effects of maternal body mass index (BMI) and gestational weight gain on maternal and neonatal outcomes in twin pregnancies. Methods: Five hundred cases of twin pregnancies were divided into a low body weight group (68 cases), a normal weight group (355 cases), an overweight group (65 cases), and an obesity group (12 cases) according to the World Health Organization (WHO) Body Mass Index (BMI) classification guidelines Results: Comparison of weight gain during different pregnancies revealed that pregnant women were mainly of low weight and average weight. The higher the BMI before pregnancy, the higher the incidence of excessive weight gain during pregnancy. The incidences of gestational diabetes mellitus (GDM) and premature rupture of membranes in women with low weight gain were significantly higher than those in women with average weight gain and high weight gain (P < 0.05). The incidences of gestational hypertension, preeclampsia, and anemia in women with high weight gain were significantly higher than those in women with low weight gain and average weight gain (P < 0.05). The incidence of neonatal birth weight, fetal distress, and macrosomia in the high weight gain group was significantly higher than those in the low weight gain and average weight gain groups (P < 0.05). The birth weight of newborns in low-weight gain mothers was significantly lower than that of normal-weight gain mothers (P < 0.05). Conclusion: Poor maternal and infant outcomes were common in women with insufficient or excessive weight gain during pregnancy. Therefore, for women with twin pregnancies, weight management is crucial to ensure maternal and infant health.

Analysis of the Effectiveness of Clopidogrel Combined with Aspirin in the Treatment of Coronary Heart Disease in Community-Dwelling Elderly

Wenling Wang — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To analyze the combined therapeutic effect of clopidogrel (CLO) and aspirin (ASP) on coronary heart disease (CHD) in community-dwelling elderly. Methods: Thirty elderly patients with CHD who were admitted to the Xinxin Community Health Service Station, Pangzhuang Street, Quanshan District, Xuzhou City, from November 2020 to November 2022 were selected and randomly grouped into an observation group and a control group, with 15 cases in each group. The observation group was given the combination of CLO and ASP and the reference group was given only ASP. The total effective rate and other treatment indicators between the two groups were compared. Results: The total effective rate of the observation group (93.33%) was higher than that of the reference group (60.00%) (P < 0.05). The adverse drug reaction rate (13.33%) and long-term cardiovascular adverse event rate (6.67%) of the observation group were lower than those of the reference group at 46.67% and 40.00% respectively, (P < 0.05). Before treatment, the two groups had no difference in the quality-of-life scores (P > 0.05). After treatment, the quality-of-life scores of the observation group were higher than those of the reference group (P < 0.05). Conclusion: CLO combined with ASP improved the therapeutic effect of community-dwelling elderly patients with CHD, reduced adverse reactions during medication, prevented adverse cardiovascular events, and comprehensively improved the patient’s quality of life.

Application of PDCA Cycle in Hand Hygiene Management of Psychiatric Medical Staff

Li Xiang, Weidong Liu, Guiying Chen, Mei Liu — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To study the application effect of the plan-do-check-act (PDCA) cycle management in the hand hygiene management of psychiatric medical staff. Methods: One hundred and twenty medical staff from a psychiatric hospital from May 2023 to December 2023 were selected and divided into two groups. The control group (May 2023 to August 2023) applied the conventional management model, and the observation group (September 2023 to December 2023) applied the PDCA cycle management. The hand hygiene compliance, hand hygiene knowledge, and hygiene qualifications were compared, including the amount of hand sanitizer used. Results: The proportion of medical staff’s hand hygiene compliance and hand hygiene knowledge mastery scores in the observation group were higher than those in the control group (P < 0.05); the hand hygiene passing rate in the observation group was higher than that of the control group (P < 0.05); the daily amount of hand sanitizer per patient bed and the amount of hand sanitizer used was higher than that of the control group (P < 0.05). Conclusion: The PDCA cycle management model for psychiatric medical staff promoted the improvement of hand hygiene compliance and increased their hand hygiene qualifications. It is suitable for further popularization and application in future clinical practice.

Analgesic Effect of Combined Spinal-Epidural Anesthesia and its Effect on TNF-α and CRP Levels in Elderly Patients with Hip Fracture During Surgical Treatment

Jie Xu, Linyan Li, Ning Wang — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To observe the analgesic effect of combined spinal and epidural anesthesia on older patients undergoing hip fracture surgery. Method: One hundred and twenty elderly hip fracture surgery patients treated in our hospital from January 2021 to December 2022 were selected and randomly divided into two groups, with 60 cases in the experimental group and 60 in the control group. The experimental group was given combined spinal-epidural anesthesia intervention measures, while the control group was given epidural anesthesia intervention measures. The analgesic effect, tumor necrosis factor-alpha (TNF-α), C-reactive protein (CRP) levels, and other observation indicators were analyzed after anesthesia intervention. Result: After the intervention, the analgesic effect and the evaluation results of the subjects in the experimental group were better than those in the control group (P < 0.05); the obtained values of TNF-α and CRP levels in the experimental group were higher than those of the control group (P < 0.05). Conclusion: The combined spinal- epidural anesthesia intervention demonstrated positive outcomes. The analgesic effect of patients during surgery and their inflammatory factor levels improved, which makes this intervention worthy of clinical application and promotion.

Clinical Observation of Chinese Medicinal Prescriptions for Swelling and Pain in The Postoperative Treatment of Mixed Hemorrhoids

Yuru Duan, Guangliang Xu, Lei Ge, Wei Zhang, Xu Zhang, Yi Yang — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To observe the clinical effect of traditional Chinese medicine (TCM) on reducing swelling and pain in patients with mixed hemorrhoids. Methods: Sixty patients with mixed hemorrhoids who were admitted to the Hospital of Traditional Chinese Medicine of Qiqihar from January 2023 to January 2024 were selected and divided into two groups. The treatment group (n = 30) was treated with mixed hemorrhoid ligation combined with traditional Chinese swelling and pain medicine, and the control group (n = 30) was only treated with mixed hemorrhoid ligation. The pain level, edema score, and prognosis of the two groups after the intervention were analyzed. The clinical efficacy was used as the evaluation criterion to compare the clinical effects of different treatment options. Results: After the treatment, the pain score, edema score, and prognostic wound score of the treatment group were all lower than those of the control group (P < 0.05). The total clinical effectiveness of the treatment group (100%) was higher than that of the control group (76.67%), (χ² = 4.2857, P < 0.05). Conclusion: The application of traditional Chinese swelling and pain medicine in treating patients with mixed hemorrhoids effectively reduced the patient’s pain, reduced the degree of wound edema, promoted wound healing, and improved the patient’s prognosis. The curative effect was significant and had a positive impact.

Analysis of the Effectiveness of Modified Non-Traumatic Filling Technology in the Treatment of Pediatric Dental Caries

Yi Liu — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To analyze the effectiveness of modified non-traumatic filling technology in the treatment of pediatric dental caries. Methods: Ninety-seven children with dental caries who were treated in our hospital (Panyu Maternal and Child Care Service Center of Guangzhou) from January 2022 to December 2023 were selected and randomly divided into two groups, with 48 cases in the experimental group and 49 in the control group. The experimental group was treated with modified non-traumatic filling techniques, while the control group was treated with conventional filling techniques. Observation indicators such as the total effectiveness of the treatment, incidence of adverse events, treatment compliance, and pain scores were analyzed after the intervention. Result: After intervention, the total effectiveness of the treatment in the experimental group was higher than that in the control group (P < 0.05). The incidence of adverse events in the experimental group was lower than that of the control group (P < 0.05). The treatment compliance of patients in the experimental group was higher than that in the control group (P < 0.05). The pain score of the experimental group was lower than that of the control group (P < 0.05). Conclusion: The application of modified non-traumatic filling technology in the treatment of pediatric dental caries showed good therapeutic outcomes. After the intervention, the child’s symptoms were significantly alleviated, the incidence of adverse events such as filling material falling off was reduced, their compliance was improved, and the pain was relieved. This procedure is worth to be promoted for clinical application.

Analysis of the Effects of Local Injection of Epinephrine and Lidocaine on Postoperative Pain and Bleeding in Children Undergoing Tonsillectomy

Ruijue Li — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To explore the effects of local injection of epinephrine and lidocaine on postoperative pain and bleeding in children undergoing tonsillectomy. Methods: Sixty-eight children who underwent a tonsillectomy in our hospital from March 2019 to October 2020 were selected. The children were randomly divided into two groups of 34 cases each. The observation group received local anesthetic injections of lidocaine and the control group received local anesthetic injections of epinephrine. The postoperative pain, operation time, blood pressure changes, and intraoperative blood loss of the two groups of children were observed and analyzed. Results: The postoperative pain, operation time, and intraoperative blood loss scores of the children in the observation group were 4.36 ± 0.69, 0.36 ± 0.09, and 39.36 ± 1.78 respectively, which were significantly better than those of the children in the control group (P < 0.05) at 5.36 ± 0.77, 0.79 ± 0.05, and 45.36 ± 1.56, respectively. The systolic blood pressure and diastolic blood pressure of the observation group 3 minutes before surgery and 180 minutes after surgery were no different from those of the control group (P > 0.05). Conclusion: Local injection of epinephrine and lidocaine effectively relieved postoperative pain and reduced bleeding in children undergoing tonsillectomy as compared to epinephrine alone.

Analysis of the Clinical Interventions for Falls in Elderly Patients in the Community From 2002 To 2022: A Bibliometric Analysis

Xiaoxiao Zhu, Yue Zhang, Fen Gu — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To analyze and provide a comprehensive overview of the knowledge structure and research hotspots of clinical interventions for falls in elderly patients in the community. Methods: The search for publications related to clinical interventions for falls in elderly patients in the community from 2002 to 2022 was conducted on the Web of Science Core Collection (WoSCC) database. VOSviewers, CiteSpace, and the R package “bibliometrix” were used to conduct this bibliometric analysis. Results: 2091 articles from 70 countries, primarily the United States and Australia, were included. The number of publications related to clinical interventions for falls in elderly patients is increasing yearly. The main research institutions in this field were the University of Sydney, Harvard University, and the University of California. BioMed Central (BMC) Geriatrics was the most popular journal in this field and Journals of the American Geriatrics Society was the most co-cited journal. These publications came from 8984 authors among which author Lord SR had published the most papers and author Tinetti Me had the most co-citations. The main keywords in this research field were “balance,” “exercise,” and “risk factor.” Conclusion: This was the first bibliometric study that comprehensively summarized the research hot spots and development of clinical interventions for falls in elderly patients in the community. This paper aims to provide a reference for scholars and researchers in this particular field.

Analysis of the Effectiveness of Biling Weitong Granules Combined with Trimethoprim and Vonoprazan in The Treatment of Reflux Esophagitis

Yalan Chen, Huiqing Zhang, Jingwei Kou, Huiling Yu — Fri, 29 Mar 2024 00:00:00 +0800

Objective: To analyze the effectiveness of Biling Weitong Granules (BLWTG) combined with trimethoprim and vonoprazan in treating reflux esophagitis. Methods: Sixty patients with reflux esophagitis admitted to our hospital from March 2020 to March 2023 were selected as study subjects and randomly divided into a control group and an experimental group, with 30 cases in each group. The control group received only the combination treatment of trimethoprim and vonoprazan, while the experimental group was treated with BLWTG based on the control group. The acid reflux and heartburn symptom scores, quality-of-life scores, clinical efficacy, Chinese medicine symptom incidences, and the occurrence of adverse reactions before and after treatment in the two groups were compared. Results: After treatment, the acid reflux and heartburn symptom scores of patients in the experimental group were lower than those of the treatment control group, and the quality-of-life scores were higher than those of the treatment control group (P < 0.05). The total clinical efficacy of the experimental group was 96.66%, which was significantly higher than that of the control group (73.33%, P < 0.05). After treatment, the incidence of Chinese medicine symptoms, such as nausea and vomiting, abdominal distension and abdominal pain, and loss of appetite of the patients in the experimental group were significantly lower than those of the control group (P < 0.05). During the treatment period, there was no significant difference in the incidence of adverse reactions between the two groups, which indicated that the safety of the two treatments was comparable (P > 0.05). Conclusion: BLWTG combined with trimethoprim and vonoprazan was safe and reliable in treating reflux esophagitis, effectively relieving the symptoms and improving its clinical efficacy. This treatment is worthy of popularization.

Analysis of Hospitalization Costs and Influencing Factors of AKI in Adult Patients

Sun, 24 Mar 2024 00:00:00 +0800

Objective: To investigate the economic burden of patients with acute kidney injury (AKI) by analyzing the distribution of hospitalization expenses and its influencing factors in the Affiliated Hospital of Hebei University. Methods: The hospitalization information of patients with AKI from January 2020 to January 2023 was collected and sorted through the hospital charging system and the factors affecting the total hospitalization cost were analyzed by multiple linear regression. Results: Univariate analysis showed that age, occupation, marriage, length of hospitalization, recovery of renal function, and stage of AKI had significant effects on hospitalization cost (P < 0.05). The result of the multiple linear regression analysis model showed that age (t = 4.11, P < 0.0001), length of hospitalization (t = 16.10, P < 0.0001), recovery of renal function (t = 3.26, P < 0.0001), AKI stage (t = 5.23, P = 0.002) are factors affecting the economic burden of patients with AKI. Conclusion: AKI patients should be managed according to age stratification to effectively control the progression of the disease and improve the quality of the medical services provided. This will reduce the economic burden of patients.

Evaluation of the Effectiveness of Community Pharmacy Services on Rational Medication Use in Elderly Patients with Hypertension and Diabetes

Tian Zheng, Xulin Huang, Lei Liu — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To explore the effect of community pharmacy services on rational medication use in elderly patients with hypertension and diabetes. Methods: Between November 2022 and December 2023, 80 elderly patients with hypertension and diabetes were selected and randomly divided into a control group (routine medication guidance) and an observation group (community pharmacy services), with 40 subjects each. The medication effect scores, blood pressure, blood sugar levels, and quality of life scores before and after intervention were compared between the two groups. Results: Comparison of pharmaceutical knowledge, medication compliance, and safe medication behavior scores showed that the observation group had higher scores as compared to the control group (P < 0.05); blood pressure (systolic blood pressure, diastolic blood pressure, heart rate) and blood sugar (fasting blood glucose, 2 h postprandial blood glucose, glycated hemoglobin) index levels were compared, and the observation group’s index levels were lower than those of the control group (P < 0.05); the scores of physical health, mental health, social relationships, and environment in the observation group were higher than those in the control group (P < 0.05). Conclusion: Community pharmacy services improved the rational medication effect of elderly patients with hypertension and diabetes, and improved their blood pressure, blood sugar control levels, and quality of life.

Clinical Study on the Effectiveness of Xian Fang Huo Ming Yin for Treating Cutaneous Infections and Promoting Wound Healing in Patients with Perianal Abscess

Xinjian Lu — Fri, 29 Mar 2024 00:00:00 +0800

Objective: To explore the effect of the Xian Fang Huo Ming Yin (XFHM) for treating cutaneous infections and promoting wound healing in patients with perianal abscesses. Methods: Sixty-one patients with perianal abscesses who were admitted to our hospital (Xinghua City People’s Hospital) from May 2022 to May 2023 were selected and randomly divided into two groups, a control group (30 cases) and a study group (31 cases). Both groups received surgical treatment. The control group received conventional treatment and warm water fumigation, sitz bath, and surgical dressing change after surgery, while the research group received XFHM based on the control group. XFHM was taken orally and replaced with warm water for fumigation and sitz bathing. Both groups received treatment for 4 weeks but discontinued sitz bathing after 2 weeks. Various clinical indicators between the two groups were compared. Results: The total clinical effective rate and wound recovery rate of the study group were higher than that of the control group. There were differences in the wound pain scores, surrounding tissue edema, and wound secretions at different time points. Both groups experienced wound pain. The scores of wound pain, surrounding tissue edema, and wound secretions of the study group were lower than those of the control group, 7 and 14 days after surgery. The serum interleukin 6 (IL-6), tumor necrosis factor-alpha (TNF-α) levels, and pH values of the study group were lower than those of the control group 10 days after surgery (P < 0.05). Conclusion: The application of XFHM for treating cutaneous infections and promoting wound healing in patients with perianal abscesses improved the treatment outcome, alleviated clinical symptoms, and promoted healing.

Clinical Study on the Treatment of Low Anal Fistula in Infants and Young Children by Anal Gland Excision and Virtual Hanging Procedure

Sun, 24 Mar 2024 00:00:00 +0800

Objective: To compare the efficacy of anal adenectomy with virtual hanging wire and anal fistulotomy in the treatment of low anal fistula in infants and children. Methods: 60 children with low anal fistula who were admitted to our hospital from October 2021 to March 2022 and met the inclusion criteria were randomly divided into two groups of 30 cases each; the treatment group was treated with anal adenectomy and virtual hanging wire surgery, and the control group was treated with anal fistula resection. The clinical efficacy after treatment was compared. Results: The total effective rate of both groups was 96.67% and the difference between the two groups was not statistically significant (P > 0.05). The postoperative pain score of the treatment group was lower than that of the control group (P < 0.05). The length of hospitalization and healing time of the treatment group was lower than that of the control group (P < 0.05). The anal function of the patients in both groups was normal, and there was no adverse reaction. Conclusion: Anal gland excision and virtual hanging surgery for the treatment of low anal fistula in infants and children have the advantages of mild pain, reduced length of hospitalization, short healing time, and better patient experience as compared to anal fistula excision.

Study on the Accuracy of Serum Prealbumin Level in Predicting the Prognosis of Patients with Critical Respiratory Illness

Xiang Wang, Zuozhou Xie, Jinhong Zhao, Yi Liu — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To analyze the accuracy of serum prealbumin levels in predicting the prognosis of patients with critical respiratory illness. Methods: Fifty patients with critical respiratory illness admitted to our hospital from October 2022 to September 2023 were selected and divided into an observation group and a control group after condition assessment, with 25 cases in each group. The results of cholinesterase (ChE), prealbumin (PALB), albumin (ALB), aspartate aminotransferase (AST), total protein (TP), and forced expiratory volume (FEV₁)/Predicted (Pred) of the two groups were measured. Results: The ChE levels of the observation group were lower than those of the control group, while the PALB and ALB levels of the observation group were higher than those of the control group (P < 0.05). The AST, TP, and FEV₁ /Pred levels of the observation group were higher than those in the control group (P < 0.05). Conclusion: Serum PALB levels can be used as the main indicator for prognosis in critically ill respiratory patients.

Analysis of the Effect of Implementing Humanized Care Service in Severe ICU Patients

Hongxia Wang — Fri, 29 Mar 2024 00:00:00 +0800

Objective: To analyze the effect of implementing humanized nursing service intervention for severe patients in the intensive care unit (ICU). Methods: A hundred severely ill ICU patients who were treated from January 2021 to December 2022 were selected and grouped into a control group and an observation group. The control group adopted routine nursing services and the observation group adopted humanized nursing services. The nursing outcome of the two groups was analyzed. Results: The nursing risk incidence of the observation group was lower than that of the control group (P < 0.05). The scale of comfort and nursing satisfaction in the observation group was higher than those in the control group (P < 0.05). Conclusion: The implementation of a humanized care service for ICU patients lowered nursing risk incidences and increased the physical comfort and nursing satisfaction of these patients.

A Cross-Sectional Study on The Prevalence of Anemia in Maintenance Hemodialysis and Peritoneal Dialysis Patients and Its Related Factors

Mingrong Huang — Sun, 24 Mar 2024 00:00:00 +0800

Objective: To study the prevalence of anemia, the proportion of hemoglobin (Hb) levels, the treatment methods, and the influencing factors of Hb levels in maintenance hemodialysis (MHD) and peritoneal dialysis patients. Methods: In this study, 602 patients with maintenance hemodialysis and continuous ambulatory peritoneal dialysis were enrolled from December 2020 to December 2022 in our hospital, and their medical records were collected and summarized. The main contents included the patient’s gender, age, primary disease, dialysis duration, dialysis method, the use of erythropoietic stimulating agents (ESA), intravenous iron, and laboratory tests. A Hb index exceeding 110 g/L was set as the standard for the prevalence of anemia. Results: The rate of anemia in patients undergoing blood purification was 83%. The proportion of ESA use was 84.1%, and the proportion of iron use was 76.7%, of which the proportion of intravenous iron used was 17.0%, and the proportion of folic acid used was 28.3%. Conclusion: The incidence of anemia in MHD patients was relatively high, with a low proportion of patients reaching the standard Hb levels. Risk factors include albumin (ALB) levels, iron storage, white blood cells, C-reactive protein, cholesterol, etc. Nutritional support, iron supplementation, and prevention of micro-inflammatory reactions can effectively promote the improvement of Hb indicators in dialysis patients to prevent anemia.

Verification and Application Evaluation of Intelligent Audit Rules for The UN9000 Urine Analysis System

Fri, 29 Mar 2024 00:00:00 +0800

Objective: To apply and verify the application of intelligent audit rules for urine analysis by Cui et al. Method: A total of 1139 urine samples of hospitalized patients in Tai’an Central Hospital from September 2021 to November 2021 were randomly selected, and all samples were manually microscopic examined after the detection of the UN9000 urine analysis line. The intelligent audit rules (including the microscopic review rules and manual verification rules) were validated based on the manual microscopic examination and manual audit, and the rules were adjusted to apply to our laboratory. The laboratory turnaround time (TAT) before and after the application of intelligent audit rules was compared. Result: The microscopic review rate of intelligent rules was 25.63% (292/1139), the true positive rate, false positive rate, true negative rate, and false negative rate were 27.66% (315/1139), 6.49% (74/1139), 62.34% (710/1139) and 3.51% (40/1139), respectively. The approval consistency rate of manual verification rules was 84.92% (727/856), the approval inconsistency rate was 0% (0/856), the interception consistency rate was 12.61% (108/856), and the interception inconsistency rate was 0% (0/856). Conclusion: The intelligence audit rules for urine analysis by Cui et al. have good clinical applicability in our laboratory.

Development of Human Rights-Based Practices in Psychiatry FromPeople Living With Mental Health Problems Lived Experiences DuringInvoluntary Hospitalization or Treatment

David Pelosse, Pierre Pariseau-Legault — Fri, 29 Mar 2024 00:00:00 +0800

This article presents the research protocol of an interpretative phenomenological study that aims to understand the lived experiences of coercion and human rights-based practices in psychiatry from the perspectives of people living with mental health problems during involuntary hospitalization or treatment. This qualitative study used an interpretative phenomenological analysis design. In-depth, one-on-one interviews along with a socio-demographic questionnaire were conducted with approximately 10 participants. Data analysis was followed by an iterative and hermeneutic emergence coding process. By centering human rights-based practices on the lived experiences of people living with mental health problems who encountered coercion, this study highlighted the contributing and limiting factors to the recognition of human rights in nursing practices. This study also promoted the development of nursing knowledge and practices that can significantly contribute to an individual’s recovery process.

Retrospective Case Series on The Enduring Rotational Stability of The AcrySof IQ Toric Intraocular Lens in Cataract Patients Suffering from Myopia

Jie Luo, Yang Liu, Bing Wang, Lei Li, Junyu Yang — Fri, 29 Mar 2024 00:00:00 +0800

Objective: To analyze the enduring rotational steadiness of AcrySof IQ Toric intraocular lens (IOL) in cataract patients suffering from myopia in a long-term study. Methods: A retrospective study was conducted on a case series involving 78 patients. A total of 120 eyes with an axial length (AL) ranging from 24–30 mm and corneal astigmatism ≥ 1.50 D underwent implantation of AcrySof IQ Toric IOL guided by the version navigation system. The eyes were divided into two groups based on AL. Group A included 60 eyes with high myopia (AL ≥ 26 mm), while Group B consisted of eyes with low to moderate myopia (24 mm ≤ AL < 26 mm). Data on the preoperative AL were collected. Measurements were taken for residual astigmatism, the best corrected visual acuity (BCDVA), corneal astigmatism, and IOL rotation occurring between 24- and 48-months post-surgery. The percentage of eyes with an IOL rotation of under 5° and 10° was analyzed. Results: The mean length of follow-up times was recorded as 34.27 ± 4.98, and the average rotation was 2.73 ± 1.29°. Group A exhibited a slightly higher average rotation of 2.87 ± 1.31°, compared to the rotation of 2.59 ± 1.27° observed in Group B. At both the 24–36 month and 26–48 month post-operation marks, the degree of IOL rotation did not show a statistically significant difference between the two groups, with none of the patients experiencing a rotation exceeding 10° (P > 0.05). The percentage of rotation degrees under 5° was recorded as 98.22%. After the procedure, the BCDVA was 0.13 ± 0.03 LogMAR. There was a substantial increase in the χ² value after the operation as compared to the pre-operative χ² value (χ² = 76.79). The standard deviation of preoperative corneal astigmatism was statistically significant (P < 0.05) at 2.17 ± 1.08 D. Following the surgical procedure, the remaining astigmatism was measured at 0.41 ± 0.26 D. The data showed a notable gap in statistical significance (t = 4.281, P < 0.05). Conclusion: The AcrySof Toric IOL was a reliable solution for managing corneal astigmatism in cataract patients with myopia, demonstrating excellent long-term rotational stability.

Swallowing Difficulties, Oral Symptoms, and Nutrition in Long-Term Care Elderly Residents – A Secondary Publication

Eeva Lindroos — Fri, 29 Mar 2024 00:00:00 +0800

Oral health is often impaired in people living in residential care. In older people, poor oral health is associated with functional deficits, multiple sclerosis, and memory disorders. Keeping one’s teeth healthy throughout life would promote both oral health and general health. Biting and swallowing problems in older people are also linked to oral health, limiting eating activities and requiring diet changes to softer foods that are easy to chew and swallow. This may limit dietary diversity and adequate nutrient intake. Although eating-related chewing and swallowing problems are common in institutionalized residents, they are often addressed too late, when the resident is already malnourished. Nutrition in nursing and retirement homes has been the subject of various studies since the 2000s. However, studies on swallowing and chewing difficulties are scarce and their link to adequate nutrient intake has received lesser attention ^[6,7].

Analysis of the Authenticity of Stone Medicinal Plants by DNA Barcoding

Yingmin Cen — Fri, 29 Mar 2024 00:00:00 +0800

The genus Pyrrosia belongs to the family Polypodiaceae and are medium-sized epiphytic ferns, where the dried leaves of Pyrrosia lingua, Pyrrosia sheareri, Pyrrosia lanceolata, and Pyrrosia calvata are commonly used in medicinal practice. In this study, the authenticity of the collected medicinal plant samples of Shiwei was identified with the help of DNA barcoding technology using the internal transcribed spacer 2 (ITS2) as the identifying sequence. The experimental samples were analyzed using the basic local alignment search tool (BLAST) and the authenticity of the samples was further verified with the results of similarity comparison. The results proved that the sequences of the experimentally collected samples of Pyrrosia lingua, Pyrrosia sheareri, Pyrrosia lanceolata, and Pyrrosia calvata had a similarity of more than 97% when compared with the corresponding sequences that were uploaded on the Internet.

A Study of the Treatment of Disfiguring Diseases in the “Qian Jin Fang”

Yuhan Li, Yang Zhao — Fri, 29 Mar 2024 00:00:00 +0800

Traditional Chinese medicine (TCM) has been passed down for more than 2,000 years. TCM beauty products driven by the principles of identification and treatment with various dosage forms and exhibit mild and safe efficacy are bound to become a main component of the beauty industry in the future. Xu once commented that “Qian Jin Fang” is different from the traditional prescription system, which emphasizes the use of medicines. In this paper, we mainly selected the prescriptions for the treatment of disfigurement diseases such as acne, scarring, black dryness, face hyperpigmentation, black mole, and rosacea from the article titled, “Upper Seven Orifices Disease - Facial Medicine IX” in the Bei Ji Qian Jin Yao Fang ^[1]. By studying and analyzing the original composition of the formula, understanding the etiology and pathogenesis of the disease, and exploring the characteristics of the formula concerning the efficacy of TCM, their properties, flavors, and meridians, we summarized the characteristics of the Qian Jin Fang. It is based on the external treatment of disfigurement diseases, with a wide variety of drugs, flexibility, and accuracy. This method draws upon analogies while utilizing excipients and harmonizers to focus on the combined healing approach of treatment and nourishment.

Analysis of the Nursing Effect of Hierarchical Extended Nursing Based on The Guidance of Orem’s Theory in Patients with PICC Catheterization

Haixia Zhu, Shuqiao Chen, Hui Chi — Fri, 29 Mar 2024 00:00:00 +0800

Objective: To analyze the nursing effect of hierarchical extended nursing based on the guidance of Orem’s theory in patients with peripherally inserted central (PICC) catheterization. Methods: Ninety-one patients with PICC catheterization admitted to the hospital from May 2021 to May 2023 were selected and divided into a control group and an observation group, with 45 and 46 cases, respectively. The control group received routine nursing care, while the observation group received routine nursing care combined with hierarchical extended nursing based on the guidance of Orem’s theory for 3 months. Relevant indicators between the two groups were compared. Results: The improvement degree of various indicators in the observation group after nursing was better than that of the control group (P < 0.05). Conclusion: Graded extended nursing based on the guidance of Orem’s theory improved the knowledge, belief, behavior, and self-efficacy of patients with PICC catheterization, and relieved their anxiety, depression, and other negative emotions. The nursing effect was deemed to be significant.

Anti-Diabetic Activity of an Extract of Syzygium Jambolanum – A Review

Kirubanandan Shanmugam — Fri, 29 Mar 2024 00:00:00 +0800

Syzygium jambolanum is a promising natural treatment for diabetes. The potential benefits of S jambolanum for diabetes include lowering blood sugar levels, increasing insulin sensitivity, protecting pancreatic beta cells, and slowing the absorption of glucose into the bloodstream. The anti-diabetic activity of the crude extract of S jambolanum was evaluated in L6 myotubes and the lipid deposition in tissue was measured using Nile red Staining. Nile red staining confirmed that a considerable quantity of lipids had been deposited in the tissue treated with a crude extract of S jambolanum, comparable to the quantity of lipids deposited with a standard drug known as Rosiglitazone. This study analyzed the anti-diabetic activity of a crude extract of S jambolanum to understand its potential as a feedstock for extracting bioactive constituents to screen for bioactive molecules in the treatment of diabetes.

Development and Evaluation of The Implementation of a Preceptorship Program for The Novice ICU Nurse Intensive Care Unit -A Secondary Publication

Annie Perron, Manon Champagne, Abir El-Haouly — Fri, 29 Mar 2024 00:00:00 +0800

This study focused on the development and evaluation of the implementation of a preceptorship program adapted to ICU practice in the Ab.-T. region to provide preceptors with tools to support novice nurses. This action research was made possible with the involvement of the centers, preceptors, and novice nurses throughout the development and implementation of the program. This approach enabled participants to take ownership of the training content and fully utilize various tools. The program was implemented throughout the CISSS, where this study was subsequently carried out. Several novices mentioned that the program reinforced their sense of security and made them feel more equipped to handle complex care situations. The preceptors said they were better equipped to offer clinical support and novices were better prepared to work in the ICU. It is important to evaluate the development of the novice nurses’ skills following their participation in this program and the long-term impact of this preceptorship.