Effects of Buzhong Yiqi Decoction (Middle Qi Tonifying Decoction) in the Treatment of Chronic Cervicitis of Spleen Deficiency Type
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Keywords

Modified Buzhong Yiqi Decoction (Middle Qi Tonifying Decoction)
Spleen deficiency type
Chronic cervicitis
Symptom score

DOI

10.26689/aogr.v1i1.5066

Submitted : 2023-02-26
Accepted : 2023-03-13
Published : 2023-03-28

Abstract

Objective: To observe the effects of modified Buzhong Yiqi Decoction (Middle Qi Tonifying Decoction) in the treatment of chronic cervicitis of spleen deficiency type. Methods: From May 2021 to December 2022, 80 patients from our hospital (The First People’s Hospital of Huangzhong District) were randomly divided into two groups (40 cases/group). Patients in the control group were treated with Western medicine, whereas patients in the observation group were treated with Buzhong Yiqi Decoction (Middle Qi Tonifying Decoction) on the basis of Western medicine. The effects (curative effect, traditional Chinese medicine [TCM] symptom scores, and incidence of adverse reactions) were compared between both groups. Results: Before treatment, the differences in TCM symptom scores and incidence of adverse reactions between the two groups were not statistically significant (P > 0.05). Compared with the control group, the observation group had significantly lower TCM symptom scores after treatment and higher curative effect (P < 0.05). Conclusion: For patients with chronic cervicitis of spleen deficiency type, Buzhong Yiqi Decoction (Middle Qi Tonifying Decoction) is effective. Significant improvement in symptoms is evident with the use of Buzhong Yiqi Decoction, and it has little side effects. Given its outstanding therapeutic advantages, its application should be advocated in clinical practice.

References

Xu Y, Hua Z, Yao X, et al., 2021, Clinical Efficacy of Modified Buzhong Yiqi Decoction (Middle Qi Tonifying Decoction) Combined with Erxian Decoction in the Treatment of Stress Urinary Incontinence in Perimenopausal Women. Chinese Journal of Experimental Formulas, 27(23): 125–130.

Wang Y, Fu Q, Mou Q, et al., 2022, Study on the Regulation of GSK-3?-Mediated Wnt/?-Catenin Signaling Pathway in Buzhong Yiqi Decoction (Middle Qi Tonifying Decoction)-Containing Serum to Enhance the Sensitivity of A549 Cells to Cisplatin. Chinese Journal of Immunology, 38(16): 1958–1962.

Pan L, Wang S, Sun J, et al., 2020, Exploration and Analysis of the Experience of Xue Ji of the Warming and Tonic School Using Buzhong Yiqi Decoction (Middle Qi Tonifying Decoction) in the Treatment of Surgical Diseases. Chinese Journal of Basic Medicine of Traditional Chinese Medicine, 26(2): 166–168 + 206.

Zhao Y, Ren Q, Wang Z, 2019, Clinical Study of Jiawei Ermiao Granules Combined with Xinfuning in the Treatment of Chronic Cervicitis with High-Risk HPV Persistent Infection. Chinese Medicine Herald, 25(8): 74–77.

Dou L, Liu F, Miao R, 2021, Effects of Recombinant Human Interferon A-2b on Inflammatory Factors and T Cell Subsets in Patients with Human Papillomavirus Infection and Refractory Cervicitis. Shanxi Medical Journal, 50(19): 2790–2792.

Zhao J, Lin J, Lin J, 2020, The Expression of p16 in HSIL and Cervicitis and Cervical Cancer Lesions and Its Correlation with Different HPV High-Risk Types. Chinese Journal of Preventive Medicine, 21(6): 666–670.

Chen G, Wang Z, 2019, Observation on the Curative Effect of Zhidai Fang Combined with Recombinant Human Interferon in the Treatment of Chronic Cervicitis Complicated with High-Risk HPV Infection. Chinese General Medicine, 17(2): 248–251.

Wu L, Wang L, Li H, et al., 2020, Effects of Interferon Vaginal Capsules Combined with Microwave Therapy on Cervicitis Complicated with High-Risk HPV Infection on Peripheral Blood Th17 and Treg Cells and Inflammatory Factors. Chinese Journal of Microecology, 32(12): 1454–1459.

Han Y, Zhang L, Dai Q, et al., 2019, Clinical Research on Recombinant Human Interferon ?-2b Suppository Combined with Baofukang Suppository in the Treatment of Chronic Cervicitis Complicated with High-Risk HPV Infection. Journal of North Sichuan Medical College, 34(3): 422–424.

Wang D, 2021, Efficacy Evaluation of Yiqi Huashi Jiedu Decoction Combined with Baofukang Suppository in the Treatment of Chronic Cervicitis Complicated by Spleen Deficiency and Dampness Accumulation Type Combined with HPV Infection. Chinese Practical Medicine, 16(31): 157–160.

Gan L, 2020, Effect Analysis of Yiqi Huashi Jiedu Decoction Modified Decoction in the Treatment of Chronic Cervicitis Complicated by HPV Infection due to Spleen Deficiency and Dampness Accumulation. Contemporary Medicine, 18(5): 195–196.

Zhao H, 2019, Clinical Efficacy Analysis of Modified Yiqi Huashi Jiedu Decoction as Adjuvant Treatment of Chronic Cervicitis Complicated with HPV Infection Due to Spleen Deficiency and Dampness Accumulation. Chinese Practical Medicine, 14(16): 140–142.

Zhang X, 2021, Clinical Observation on Modified Yiqi Huashi Jiedu Decoction as Adjuvant Treatment of Spleen Deficiency Dampness and Toxin Accumulation Chronic Cervicitis Complicated with HPV Infection. Medical Diet Therapy and Health, 19(15): 28–29.

Hu Y, 2020, The Effect of Modified Yiqi Huashi Jiedu Decoction Combined with Recombinant Human Interferon ?-2b in the Treatment of Patients with Chronic Cervicitis Complicated by Spleen Deficiency and Damp Toxin Accumulation Complicated with HPV Infection. China Minkang Medicine, 32(14): 88–90.

Xia B, 2020, Clinical Efficacy of Modified Yiqi Huashi Jiedu Decoction as an Adjuvant Treatment of Chronic Cervicitis Complicated by Spleen Deficiency and Damp Toxin Accumulation Combined with HPV Infection. Inner Mongolia Traditional Chinese Medicine, 39(9): 79–80.

Guan H, 2021, Clinical Observation on Treatment of Chronic Cervicitis of Spleen Deficiency and Dampness Toxin by Huashi Qingdu Method Combined with Cervical Circumcision. Guangming Traditional Chinese Medicine, 36(7): 1137–1139.